Chronic Hepatitis B
نویسنده
چکیده
The presence of antibodies to hepatitis B core antigen (anti-HBc) has a different implication than with anti-HBs. Anti-HBc antibodies do not distinguish between active or previous infection, nor to they indicate immunity. All hepatitis B carriers and all patients who have previously been exposed to hepatitis B will be positive for total anti-HBc. Chronic hepatitis B carriers have circulating anti-Hbc IgM antibodies, but depending on the sensitivity of the assa~ these may not be detected. Many laboratories test for anti-HBc when a hepatitis screen is requested, but the identification of this antibody in serum adds nothing to the management of the patient.
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